
François Morvan
134 K. Pérez de Carvasal , L. Nicollet , M. Smietana* , F. Morvan*. Stabilization of DNA Duplexes and Hairpins by Charge-Transfer Interactions Using DAN:NDI Pairs
ACS Langmuir, 2023, 39, 7418-7425. https://doi.org/10.1021/acs.langmuir.3c00619
133 K. Pérez de Carvasal; Vergoten, G.; Vasseur, J.-J.; Smietana, M.; Morvan, F. Supramolecular Recognition of Phosphodiester-Based Donor and Acceptor Oligomers Forming Gels in Water. Biomacromolecules 2023, 24, 756-765. https://doi.org/10.1021/acs.biomac.2c01203.
132 R. Troisi; Riccardi, C.; Perez de Carvasal, K.; Smietana, M.; Morvan, F.; Del Vecchio, P.; Montesarchio, D.; Sica, F. A terminal functionalization strategy reveals unusual binding abilities of anti-thrombin anticoagulant aptamers. Mol Ther Nucleic Acids 2022, 30, 585-594. https://doi.org/10.1016/j.omtn.2022.11.007.
131 A. Mills; Aissaoui, N.; Maurel, D.; Elezgaray, J.; Morvan, F.; Vasseur, J. J.; Margeat, E.; Quast, R. B.; Kee-Him, J. L.; Saint, N.et al. A modular spring-loaded actuator for mechanical activation of membrane proteins. Nat. Commun. 2022, 13, 10. https://doi.org/10.1038/s41467-022-30745-2.
130 A. Meyer; Baraguey, C.; Vasseur, J. J.; Morvan, F. Oligonucleotide Conjugation by Tyrosine-Click Reaction. Eur. J. Org. Chem. 2022, 2022, 10. https://doi.org/10.1002/ejoc.202101361.
129 F. Leon; Pinchon, E.; Mayran, C.; Daynes, A.; Morvan, F.; Moles, J. P.; Cantaloube, J. F.; Fournier-Wirth, C. Magnetic Field-Enhanced Agglutination Readout Combined With Isothermal Reverse Transcription Recombinase Polymerase Amplification for Rapid and Sensitive Molecular Detection of Dengue Virus. Front. Chem. 2022, 9, 7. https://doi.org/10.3389/fchem.2021.817246.
128 K. Perez de Carvasal; Riccardi, C.; Krauss, I. R.; Cavasso, D.; Vasseur, J. J.; Smietana, M.; Morvan, F.; Montesarchio, D. Charge-Transfer Interactions Stabilize G-Quadruplex-Forming Thrombin Binding Aptamers and Can Improve Their Anticoagulant Activity. Int. J. Mol. Sci. 2021, 22, 23. https://doi.org/10.3390/ijms22179510.
127 K. Perez de Carvasal; Aissaoui, N.; Vergoten, G.; Bellot, G.; Vasseur, J. J.; Smietana, M.; Morvan, F. Folding of phosphodiester-linked donor-acceptor oligomers into supramolecular nanotubes in water. Chem. Commun. 2021, 57, 4130-4133. https://doi.org/10.1039/d1cc01064f.
126 F. Leon; Pinchon, E.; Temurok, N.; Morvan, F.; Vasseur, J. J.; Clot, M.; Foulongne, V.; Cantaloube, J. F.; Vande Perre, P.; Moles, J. P.et al. Diagnostic Performance of a Magnetic Field-Enhanced Agglutination Readout in Detecting Either Viral Genomes or Host Antibodies in Arbovirus Infection. Microorganisms 2021, 9, 12. https://doi.org/10.3390/microorganisms9040674.
125 C. Riccardi; Meyer, A.; Vasseur, J. J.; Krauss, I. R.; Paduano, L.; Morvan, F.; Montesarchio, D. Fine-tuning the properties of the thrombin binding aptamer through cyclization: Effect of the 5 ‘-3 ‘ connecting linker on the aptamer stability and anticoagulant activity. Bioorganic Chem. 2020, 94, 14. https://doi.org/10.1016/j.bioorg.2019.103379.
124 C. Riccardi; Meyer, A.; Vasseur, J. J.; Cavasso, D.; Krauss, I. R.; Paduano, L.; Morvan, F.; Montesarchio, D. Design, Synthesis and Characterization of Cyclic NU172 Analogues: A Biophysical and Biological Insight. Int. J. Mol. Sci. 2020, 21, 26. https://doi.org/10.3390/ijms21113860.
123 E. Pinchon; Leon, F.; Temurok, N.; Morvan, F.; Vasseur, J. J.; Clot, M.; Foulongne, V.; Cantaloube, J. F.; Vande Perre, P.; Daynes, A.et al. Rapid and specific DNA detection by magnetic field-enhanced agglutination assay. Talanta 2020, 219, 6. https://doi.org/10.1016/j.talanta.2020.121344.
122 M. Madaoui; Vidal, O.; Meyer, A.; Noel, M.; Lacroix, J. M.; Vasseur, J. J.; Marra, A.; Morvan, F. Modified Galacto- or Fuco-Clusters Exploiting the Siderophore Pathway to Inhibit the LecA- or LecB-Associated Virulence ofPseudomonas aeruginosa. ChemBioChem 2020, 21, 3433-3448. https://doi.org/10.1002/cbic.202000490.
121 F. Zuttion; Sicard, D.; Dupin, L.; Vergoten, G.; Girard-Bock, C.; Madaoui, M.; Chevolot, Y.; Morvan, F.; Vidal, S.; Vasseur, J. J.et al. Deciphering multivalent glycocluster-lectin interactions through AFM characterization of the self-assembled nanostructures. Soft Matter 2019, 15, 7211-7218. https://doi.org/10.1039/c9sm00371a.
120 C. Riccardi; Meyer, A.; Vasseur, J. J.; Krauss, I. R.; Paduano, L.; Oliva, R.; Petraccone, L.; Morvan, F.; Montesarchio, D. Stability Is Not Everything: The Case of the Cyclisation of a Thrombin-Binding Aptamer. ChemBioChem 2019, 20, 1789-1794. https://doi.org/10.1002/cbic.201900045.
119 M. Noel; Clement-Blanc, C.; Meyer, A.; Vasseur, J. J.; Morvan, F. Solid Supports for the Synthesis of 3 ‘-Aminooxy Deoxy- or Ribo-oligonucleotides and Their 3 ‘-Conjugation by Oxime Ligation. J. Org. Chem. 2019, 84, 14854-14860. https://doi.org/10.1021/acs.joc.9b00848.
118 M. Madaoui; Meyer, A.; Vasseur, J. J.; Morvan, F. Thermolytic Reagents to Synthesize 5-or 3-Mono(thio)phosphate Oligodeoxynucleotides or 3-modified oligodeoxynucleotides. Eur. J. Org. Chem. 2019, 2019, 2832-2842. https://doi.org/10.1002/ejoc.201900302.
117 F. Leon; Meyer, A.; Reynier, R.; Blanc, E.; Bruyere-Ostells, L.; Bres, J. C.; Simonin, Y.; Salinas, S.; Gallian, P.; Leparc-Goffart, I.et al. An Innovative Multiplexed and Flexible Molecular Approach for the Differential Detection of Arboviruses. J. Mol. Diagn. 2019, 21, 81-88. https://doi.org/10.1016/j.jmoldx.2018.08.005.
116 F. Zuttion; Ligeour, C.; Vidal, O.; Walte, M.; Morvan, F.; Vidal, S.; Vasseur, J. J.; Chevolot, Y.; Phaner-Goutorbe, M.; Schillers, H. The anti-adhesive effect of glycoclusters on Pseudomonas aeruginosa bacteria adhesion to epithelial cells studied by AFM single cell force spectroscopy. Nanoscale 2018, 10, 12771-12778. https://doi.org/10.1039/c8nr03285h.
115 L. Dupin; Noel, M.; Bonnet, S.; Meyer, A.; Gehin, T.; Bastide, L.; Randriantsoa, M.; Souteyrand, E.; Cottin, C.; Vergoten, G.et al. Screening of a Library of Oligosaccharides Targeting Lectin LecB of Pseudomonas Aeruginosa and Synthesis of High Affinity Oligoglycoclusters. Molecules 2018, 23, 24. https://doi.org/10.3390/molecules23123073.
114 C. Riccardi; Krauss, I. R.; Musumeci, D.; Morvan, F.; Meyer, A.; Vasseur, J. J.; Paduano, L.; Montesarchio, D. Fluorescent Thrombin Binding Aptamer-Tagged Nanoparticles for an Efficient and Reversible Control of Thrombin Activity. ACS Appl. Mater. Interfaces 2017, 9, 35574-35587. https://doi.org/10.1021/acsami.7b11195.
113 A. Meyer; Vasseur, J. J.; Dumy, P.; Morvan, F. Phthalimide-Oxy Derivatives for 3-or 5-Conjugation of Oligonucleotides by Oxime Ligation and Circularization of DNA by “Bis- or Tris-Click” Oxime Ligation. Eur. J. Org. Chem. 2017, 2017, 6931-6941. https://doi.org/10.1002/ejoc.201701317.
112 M. J. Banuls; Jimenez-Meneses, P.; Meyer, A.; Vasseur, J. J.; Morvan, F.; Escorihuela, J.; Puchades, R.; Maquieira, A. Improved Performance of DNA Microarray Multiplex Hybridization Using Probes Anchored at Several Points by Thiol-Ene or Thiol-Yne Coupling Chemistry. Bioconjugate Chem. 2017, 28, 496-506. https://doi.org/10.1021/acs.bioconjchem.6b00624.
111 A. Angeli; Li, M. C.; Dupin, L.; Vergoten, G.; Noel, M.; Madaoui, M.; Wang, S.; Meyer, A.; Gehin, T.; Vidal, S.et al. Design and Synthesis of Galactosylated Bifurcated Ligands with Nanomolar Affinity for Lectin LecA from Pseudomonas aeruginosa. ChemBioChem 2017, 18, 1036-1047. https://doi.org/10.1002/cbic.201700154.
110 A. Angeli; Dupin, L.; Madaoui, M.; Li, M. C.; Vergoten, G.; Wang, S.; Meyer, A.; Gehin, T.; Vidal, S.; Vasseur, J. J.et al. Glycoclusters with Additional Functionalities for Binding to the LecA Lectin from Pseudomonas aeruginosa. ChemistrySelect 2017, 2, 10420-10427. https://doi.org/10.1002/slct.201702131.
109 S. Wang; Dupin, L.; Noel, M.; Carroux, C. J.; Renaud, L.; Gehin, T.; Meyer, A.; Souteyrand, E.; Vasseur, J. J.; Vergoten, G.et al. Toward the Rational Design of Galactosylated Glycoclusters That Target Pseudomonas aeruginosa Lectin A (LecA): Influence of Linker Arms That Lead to Low-Nanomolar Multivalent Ligands. Chem.-Eur. J. 2016, 22, 11785-11794. https://doi.org/10.1002/chem.201602047.
108 A. Meyer; Noel, M.; Vasseur, J. J.; Morvan, F. Hetero-Click Conjugation of Oligonucleotides with Glycosides Using Bifunctional Phosphoramidites. Eur. J. Org. Chem. 2015, 2015, 2921-2927. https://doi.org/10.1002/ejoc.201500165.
107 C. Ligeour; Vidal, O.; Dupin, L.; Casoni, F.; Gillon, E.; Meyer, A.; Vidal, S.; Vergoten, G.; Lacroix, J. M.; Souteyrand, E.et al. Mannose-centered aromatic galactoclusters inhibit the biofilm formation of Pseudomonas aeruginosa. Org. Biomol. Chem. 2015, 13, 8433-8444. https://doi.org/10.1039/c5ob00948k.
106 C. Ligeour; Dupin, L.; Angeli, A.; Vergoten, G.; Vidal, S.; Meyer, A.; Souteyrand, E.; Vasseur, J. J.; Chevolot, Y.; Morvan, F. Importance of topology for glycocluster binding to Pseudomonas aeruginosa and Burkholderia ambifaria bacterial lectins. Org. Biomol. Chem. 2015, 13, 11244-11254. https://doi.org/10.1039/c5ob01445j.
105 S. Estalayo-Adrian; Lartia, R.; Meyer, A.; Vasseur, J. J.; Morvan, F.; Defrancq, E. Assessment of the Full Compatibility of Copper(I)-Catalyzed Alkyne-Azide Cycloaddition and Oxime Click Reactions for bis-Labelling of Oligonucleotides. ChemistryOpen 2015, 4, 169-173. https://doi.org/10.1002/open.201402099.
104 L. Dupin; Zuttion, F.; Gehin, T.; Meyer, A.; Phaner-Goutorbe, M.; Vasseur, J. J.; Souteyrand, E.; Morvan, F.; Chevolot, Y. Effects of the Surface Densities of Glycoclusters on the Determination of Their IC50 and K-d Value Determination by Using a Microarray. ChemBioChem 2015, 16, 2329-2336. https://doi.org/10.1002/cbic.201500371.
103 C. Ligeour; Dupin, L.; Marra, A.; Vergoten, G.; Meyer, A.; Dondoni, A.; Souteyrand, E.; Vasseur, J. J.; Chevolot, Y.; Morvan, F. Synthesis of Galactoclusters by Metal-Free Thiol “Click Chemistry” and Their Binding Affinities for Pseudomonas aeruginosa Lectin LecA. Eur. J. Org. Chem. 2014, 2014, 7621-7630. https://doi.org/10.1002/ejoc.201402902.
102 B. Gerland; Goudot, A.; Ligeour, C.; Pourceau, G.; Meyer, A.; Vidal, S.; Gehin, T.; Vidal, O.; Souteyrand, E.; Vasseur, J. J.et al. Structure Binding Relationship of Galactosylated Glycoclusters toward Pseudomonas aeruginosa Lectin LecA Using a DNA-Based Carbohydrate Microarray. Bioconjugate Chem. 2014, 25, 379-392. https://doi.org/10.1021/bc4005365.
101 Y. Chevolot; Laurenceau, E.; Phaner-Goutorbe, M.; Monnier, V.; Souteyrand, E.; Meyer, A.; Gehin, T.; Vasseur, J. J.; Morvan, F. DNA directed immobilization glycocluster array: applications and perspectives. Curr. Opin. Chem. Biol. 2014, 18, 46-54. https://doi.org/10.1016/j.cbpa.2013.12.009.
100 F. Casoni; Dupin, L.; Vergoten, G.; Meyer, A.; Ligeour, C.; Gehin, T.; Vidal, O.; Souteyrand, E.; Vasseur, J. J.; Chevolot, Y.et al. The influence of the aromatic aglycon of galactoclusters on the binding of LecA: a case study with O-phenyl, S-phenyl, O-benzyl, S-benzyl, O-biphenyl and O-naphthyl aglycons. Org. Biomol. Chem. 2014, 12, 9166-9179. https://doi.org/10.1039/c4ob01599a.
99 N. Spinelli; Defrancq, E.; Morvan, F. Glycoclusters on oligonucleotide and PNA scaffolds: synthesis and applications. Chem. Soc. Rev. 2013, 42, 4557-4573. https://doi.org/10.1039/c2cs35406c.
98 A. Meyer; Vasseur, J. J.; Morvan, F. Synthesis of Monoconjugated and Multiply Conjugated Oligonucleotides by “Click Thiol” Thiol-Michael-Type Additions and by Combination with CuAAC “Click Huisgen”. Eur. J. Org. Chem. 2013, 2013, 465-473. https://doi.org/10.1002/ejoc.201201311.
97 C. Ligeour; Audfray, A.; Gillon, E.; Meyer, A.; Galanos, N.; Vidal, S.; Vasseur, J. J.; Imberty, A.; Morvan, F. Synthesis of branched-phosphodiester and mannose-centered fucosylated glycoclusters and their binding studies with Burkholderia ambifaria lectin (BambL). RSC Adv. 2013, 3, 19515-19524. https://doi.org/10.1039/c3ra43807d.
96 M. Lereau; Fournier-Wirth, C.; Mayen, J.; Farre, C.; Meyer, A.; Dugas, V.; Cantaloube, J. F.; Chaix, C.; Vasseur, J. J.; Morvan, F. Development of Innovative and Versatile Polythiol Probes for Use on ELOSA or Electrochemical Biosensors: Application in Hepatitis C Virus Genotyping. Anal. Chem. 2013, 85, 9204-9212. https://doi.org/10.1021/ac401941x.
95 A. Goudot; Pourceau, G.; Meyer, A.; Gehin, T.; Vidal, S.; Vasseur, J. J.; Morvan, F.; Souteyrand, E.; Chevolot, Y. Quantitative analysis (K-d and IC50) of glycoconjugates interactions with a bacterial lectin on a carbohydrate microarray with DNA Direct Immobilization (DDI). Biosens. Bioelectron. 2013, 40, 153-160. https://doi.org/10.1016/j.bios.2012.07.003.
94 S. De Tito; Morvan, F.; Meyer, A.; Vasseur, J. J.; Cummaro, A.; Petraccone, L.; Pagano, B.; Novellino, E.; Randazzo, A.; Giancola, C.et al. Fluorescence Enhancement upon G-Quadruplex Folding: Synthesis, Structure, and Biophysical Characterization of a Dansyl/Cyclodextrin-Tagged Thrombin Binding Aptamer. Bioconjugate Chem. 2013, 24, 1917-1927. https://doi.org/10.1021/bc400352s.
93 Y. Thillier; Decroly, E.; Morvan, F.; Canard, B.; Vasseur, J. J.; Debart, F. Synthesis of 5 ‘ cap-0 and cap-1 RNAs using solid-phase chemistry coupled with enzymatic methylation by human (guanine-N-7)-methyl transferase. Rna 2012, 18, 856-868. https://doi.org/10.1261/rna.030932.111.
92 F. Morvan; Vidal, S.; Souteyrand, E.; Chevolot, Y.; Vasseur, J. J. DNA glycoclusters and DNA-based carbohydrate microarrays: From design to applications. RSC Adv. 2012, 2, 12043-12068. https://doi.org/10.1039/c2ra21550k.
91 C. Ligeour; Meyer, A.; Vasseur, J. J.; Morvan, F. Bis- and Tris-Alkyne Phosphoramidites for Multiple 5′-Labeling of Oligonucleotides by Click Chemistry. Eur. J. Org. Chem. 2012, 2012, 1851-1856. https://doi.org/10.1002/ejoc.201101763.
90 M. Iazykov; Sicard, D.; Chevolot, Y.; Souteyrand, E.; Phaner-Goutorbe, M.; Skryshevsky, V. A.; Pourceau, G.; Vasseur, J. J.; Morvan, F. Self-assembly architectures of new DNA-based structures in air and in liquids analyzed by atomic force microscopy. Int. J. Nanosci. 2012, 11, 1240017. https://doi.org/10.1142/s0219581x12400170.
89 B. Gerland; Goudot, A.; Pourceau, G.; Meyer, A.; Vidal, S.; Souteyrand, E.; Vasseur, J. J.; Chevolot, Y.; Morvan, F. Synthesis of Homo- and Heterofunctionalized Glycoclusters and Binding to Pseudomonas aeruginosa Lectins PA-IL and PA-IIL. J. Org. Chem. 2012, 77, 7620-7626. https://doi.org/10.1021/jo300826u.
88 B. Gerland; Goudot, A.; Pourceau, G.; Meyer, A.; Dugas, V.; Cecioni, S.; Vidal, S.; Souteyrand, E.; Vasseur, J. J.; Chevolot, Y.et al. Synthesis of a Library of Fucosylated Glycoclusters and Determination of their Binding toward Pseudomonas aeruginosa Lectin B (PA-IIL) Using a DNA-Based Carbohydrate Microarray. Bioconjugate Chem. 2012, 23, 1534-1547. https://doi.org/10.1021/bc2006434.
87 G. Pourceau; Chevolot, Y.; Goudot, A.; Giroux, F.; Meyer, A.; Moules, V.; Lina, B.; Cecioni, S.; Vidal, B.; Yu, H.et al. Measurement of Enzymatic Activity and Specificity of Human and Avian Influenza Neuraminidases from Whole Virus by Glycoarray and MALDI-TOF Mass Spectrometry. ChemBioChem 2011, 12, 2071-2080. https://doi.org/10.1002/cbic.201100128.
86 Y. Chevolot; Zhang, J.; Meyer, A.; Goudot, A.; Rouanet, S.; Vidal, S.; Pourceau, G.; Cloarec, J. P.; Praly, J. P.; Souteyrand, E.et al. Multiplexed binding determination of seven glycoconjugates for Pseudomonas aeruginosa Lectin I (PA-IL) using a DNA-based carbohydrate microarray. Chem. Commun. 2011, 47, 8826-8828. https://doi.org/10.1039/c1cc12428e.
85 G. Chatelain; Meyer, A.; Morvan, F.; Vasseur, J. J.; Chaix, C. Electrochemical detection of nucleic acids using pentaferrocenyl phosphoramidate alpha-oligonucleotides. New J. Chem. 2011, 35, 893-901. https://doi.org/10.1039/c0nj00902d.
84 I. Zlatev; Lavergne, T.; Debart, F.; Vasseur, J. J.; Manoharan, M.; Morvan, F. Efficient Solid-Phase Chemical Synthesis of 5 ‘-Triphosphates of DNA, RNA, and their Analogues. Org. Lett. 2010, 12, 2190-2193. https://doi.org/10.1021/ol1004214.
83 S. Priet; Zlatev, I.; Barvik, I.; Geerts, K.; Leyssen, P.; Neyts, J.; Dutartre, H.; Canard, B.; Vasseur, J. J.; Morvan, F.et al. 3 ‘-Deoxy Phosphoramidate Dinucleosides as Improved Inhibitors of Hepatitis C Virus Subgenomic Replicon and NS5B Polymerase Activity. J. Med. Chem. 2010, 53, 6608-6617. https://doi.org/10.1021/jm100102v.
82 G. Pourceau; Meyer, A.; Chevolot, Y.; Souteyrand, E.; Vasseur, J. J.; Morvan, F. Oligonucleotide Carbohydrate-Centered Galactosyl Cluster Conjugates Synthesized by Click and Phosphoramidite Chemistries. Bioconjugate Chem. 2010, 21, 1520-1529. https://doi.org/10.1021/bc1001888.
81 F. Morvan; Debart, F.; Vasseur, J. J. From Anionic to Cationic alpha-Anomeric Oligodeoxynucleotides. Chem. Biodivers. 2010, 7, 494-535. https://doi.org/10.1002/cbdv.200900220.
80 A. Meyer; Spinelli, N.; Dumy, P.; Vasseur, J. J.; Morvan, F.; Defrancq, E. Oligonucleotide Sequential Bis-Conjugation via Click-Oxime and Click-Huisgen Procedures. J. Org. Chem. 2010, 75, 3927-3930. https://doi.org/10.1021/jo.100599m.
79 A. Meyer; Pourceau, G.; Vasseur, J. J.; Morvan, F. 5 ‘-Bis-conjugation of Oligonucleotides by Amidative Oxidation and Click Chemistry. J. Org. Chem. 2010, 75, 6689-6692. https://doi.org/10.1021/jo101134z.
78 I. Zlatev; Giraut, A.; Morvan, F.; Herdewijn, P.; Vasseur, J. J. delta-Di-carboxybutyl phosphoramidate of 2 ‘-deoxycytidine-5 ‘-monophosphate as substrate for DNA polymerization by HIV-1 reverse transcriptase. Bioorg. Med. Chem. 2009, 17, 7008-7014. https://doi.org/10.1016/j.bmc.2009.08.001.
77 J. Zhang; Pourceau, G.; Meyer, A.; Vidal, S.; Praly, J. P.; Souteyrand, E.; Vasseur, J. J.; Morvan, F.; Chevolot, Y. Specific recognition of lectins by oligonucleotide glycoconjugates and sorting on a DNA microarray. Chem. Commun. 2009, DOI:10.1039/b915132j 10.1039/b915132j, 6795-6797. https://doi.org/10.1039/b915132j.
76 J. Zhang; Pourceau, G.; Meyer, A.; Vidal, S.; Praly, J. P.; Souteyrand, E.; Vasseur, J. J.; Morvan, F.; Chevolot, Y. DNA-directed immobilisation of glycomimetics for glycoarrays application: Comparison with covalent immobilisation, and development of an on-chip IC50 measurement assay. Biosens. Bioelectron. 2009, 24, 2515-2521. https://doi.org/10.1016/j.bios.2009.01.007.
75 G. Pourceau; Meyer, A.; Vasseur, J. J.; Morvan, F. Synthesis of Mannose and Galactose Oligonucleotide Conjugates by Bi-click chemistry. J. Org. Chem. 2009, 74, 1218-1222. https://doi.org/10.1021/jo802536q.
74 G. Pourceau; Meyer, A.; Vasseur, J. J.; Morvan, F. Azide Solid Support for 3 ‘-Conjugation of Oligonucleotides and Their Circularization by Click Chemistry. J. Org. Chem. 2009, 74, 6837-6842. https://doi.org/10.1021/jo9014563.
73 L. Moni; Pourceau, G.; Zhang, J.; Meyer, A.; Vidal, S.; Souteyrand, E.; Dondoni, A.; Morvan, F.; Chevolot, Y.; Vasseur, J. J.et al. Design of Triazole-Tethered Glycoclusters Exhibiting Three Different Spatial Arrangements and Comparative Study of their Affinities towards PA-IL and RCA 120 by Using a DNA-Based Glycoarray. ChemBioChem 2009, 10, 1369-1378. https://doi.org/10.1002/cbic.200900024.
72 I. Zlatev; Vasseur, J. J.; Morvan, F. O. Deoxygenation of 5-O-benzoyl-1,2-isopropylidene-3-O-imidazolylthiocarbonyl-alpha-D-xylofu ranose using dimethyl phosphite: an efficient alternate method towards a 3′-deoxynucleoside glycosyl donor. Tetrahedron Lett. 2008, 49, 3288-3290. https://doi.org/10.1016/j.tetlet.2008.03.079.
71 I. Zlatev; Dutartre, H.; Barvik, I.; Neyts, J.; Canard, B.; Vasseur, J. J.; Alvarez, K.; Morvan, F. Phosphoramidate dinucleosides as hepatitis C virus polymerase inhibitors. J. Med. Chem. 2008, 51, 5745-5757. https://doi.org/10.1021/jm800617c.
70 G. Pourceau; Meyer, A.; Vasseur, J. J.; Morvan, F. Combinatorial and automated synthesis of phosphodiester galactosyl cluster on solid support by click chemistry assisted by microwaves. J. Org. Chem. 2008, 73, 6014-6017. https://doi.org/10.1021/jo8009837.
69 J. Lietard; Meyer, A.; Vasseur, J. J.; Morvan, F. New strategies for cyclization and bicyclization of oligonucleotides by click chemistry assisted by microwaves. J. Org. Chem. 2008, 73, 191-200. https://doi.org/10.1021/jo702177c.
68 I. Zlatev; Vasseur, J. J.; Morvan, F. Convenient synthesis of N-2-isobutyryl-2′-O-methyl guanosine by efficient alkylation of O-6-trimethylsilylethyl-3′,5′-di-tert-butylsilanediyl guanosine. Tetrahedron 2007, 63, 11174-11178. https://doi.org/10.1016/j.tet.2007.08.006.
67 F. Morvan; Meyer, A.; Jochum, A.; Sabin, C.; Chevolot, Y.; Imberty, A.; Praly, J. P.; Vasseur, J. J.; Souteyrand, E.; Vidal, S. Fucosylated pentaerythrityl phosphodiester oligomers (PePOs): Automated synthesis of DNA-Based glycoclusters and binding to Pseudomonas aeruginosa lectin (PA-IIL). Bioconjugate Chem. 2007, 18, 1637-1643. https://doi.org/10.1021/bc070129z.
66 J. Lietard; Meyer, A.; Vasseur, J. J.; Morvan, F. An efficient reagent for 5 ‘-azido oligonucleotide synthesis. Tetrahedron Lett. 2007, 48, 8795-8798. https://doi.org/10.1016/j.tetlet.2007.10.081.
65 M. Froeyen; Morvan, F.; Vasseur, J. J.; Nielsen, P.; Van Aerschot, A.; Rosemeyer, H.; Herdewijn, P. Conformational and chiral selection of oligonucleotides. Chem. Biodivers. 2007, 4, 803-817. https://doi.org/10.1002/cbdv.200790065.
64 G. Deglane; Morvan, F.; Debart, F.; Vasseur, J. J. 5-Propynylamino alpha-deoxyuridine promotes DNA duplex stabilization of anionic and neutral but not cationic alpha-oligonucleotides. Bioorg. Med. Chem. Lett. 2007, 17, 951-954. https://doi.org/10.1016/j.bmcl.2006.11.052.
63 Y. Chevolot; Bouillon, C.; Vidal, S.; Morvan, F.; Meyer, A.; Cloarec, J. P.; Jochum, A.; Praly, J. P.; Vasseur, J. J.; Souteyrand, E. DNA-based carbohydrate biochips: A platform for surface glyco-engineering. Angew. Chem.-Int. Edit. 2007, 46, 2398-2402. https://doi.org/10.1002/anie.200604955.
62 I. Zlatev; Kato, Y.; Meyer, A.; Vasseur, J. J.; Morvan, F. Use of a solid-supported coupling reagent for a selective phosphitylation of the primary alcohol of N-2-isobutyryl-2 ‘-deoxy or 2 ‘-O-methyl guanosine. Tetrahedron Lett. 2006, 47, 8379-8382. https://doi.org/10.1016/j.tetlet.2006.09.086.
61 A. Meyer; Bouillon, C.; Vidal, S.; Vasseur, J. J.; Morvan, F. A versatile reagent for the synthesis of 5 ‘-phosphorylated, 5 ‘-thiophosphorylated or 5 ‘-phosphoramidate-conjugated oligonucleotides. Tetrahedron Lett. 2006, 47, 8867-8871. https://doi.org/10.1016/j.tetlet.2006.10.049.
60 C. Bouillon; Meyer, A.; Vidal, S.; Jochum, A.; Chevolot, Y.; Cloarec, J. P.; Praly, J. P.; Vasseur, J. J.; Morvan, F. Microwave assisted “click” chemistry for the synthesis of multiple labeled-carbohydrate oligonucleotides on solid support. J. Org. Chem. 2006, 71, 4700-4702. https://doi.org/10.1021/jo060572n.
59 I. Adamo; Dueymes, U.; Schonberger, A.; Navarro, A. E.; Meyer, A.; Lange, M.; Imbach, J. L.; Link, F.; Morvan, F.; Vasseur, J. J. Solution-phase synthesis of phosphorothioate oligonucleotides using a solid-supported acyl chloride with H-phosphonate chemistry. Eur. J. Org. Chem. 2006, 2006, 436-448. https://doi.org/10.1002/ejoc.200500547.
58 C. Goussu; Vasseur, J. J.; Bazin, H.; Trinquet, E.; Maurin, F.; Morvan, F. Optimized synthesis of functionalized fluorescent oligodeoxynucleotides for protein labeling. Bioconjugate Chem. 2005, 16, 465-470. https://doi.org/10.1021/bc049752z.
57 F. Ferreira; Meyer, A.; Vasseur, J. J.; Morvan, F. Universal solid supports for the synthesis of oligonucleotides via a transesterification of H-phosphonate diester linkage. J. Org. Chem. 2005, 70, 9198-9206. https://doi.org/10.1021/jo051172n.
56 C. Dueymes; Schonberger, A.; Adamo, I.; Navarro, A. E.; Meyer, A.; Lange, M.; Imbach, J. L.; Link, F.; Morvan, F.; Vasseur, J. J. High-yield solution-phase synthesis of Di- and trinucleotide blocks assisted by polymer-supported reagents. Org. Lett. 2005, 7, 3485-3488. https://doi.org/10.1021/ol0511777.
55 A. Meyer; Morvan, F.; Vasseur, J. J. H-Phosphonate oligonucleotides from phosphoramidite chemistry. Tetrahedron Lett. 2004, 45, 3745-3748. https://doi.org/10.1016/j.tetlet.2004.03.093.
54 F. Ferreira; Vasseur, J. J.; Morvan, F. Lewis acid deprotection of silyl-protected oligonucleotides and base-sensitive oligonucleotide analogues. Tetrahedron Lett. 2004, 45, 6287-6290. https://doi.org/10.1016/j.tetlet.2004.06.081.
53 T. Guerlavais-Dagland; Meyer, A.; Imbach, J. L.; Morvan, F. Fluoride-labile protecting groups for the synthesis of base-sensitive methyl-SATE oligonucleotide prodrugs. Eur. J. Org. Chem. 2003, 2003, 2327-2335. https://doi.org/10.1002/ejoc.200300069.
52 T. Guerlavais-Dagland; Meyer, A.; Morvan, F. Efficient and low cost synthesis of the 2-(tert-butyldiphenylsilyloxymethyl) benzoyl chloride for the protection of nucleobases. J. Chem. Res 2002, 606-607.
51 T. Guerlavais; Meyer, A.; Debart, F.; Imbach, J. L.; Morvan, F.; Vasseur, J. J. Use of MALDI-TOF mass spectrometry to monitor solid-phase synthesis of oligonucleotides. Anal. Bioanal. Chem. 2002, 374, 57-63. https://doi.org/10.1007/s00216-002-1395-7.
50 S. Drioli; Adamo, A.; Ballico, M.; Morvan, F.; Bonora, G. M. Liquid-phase synthesis and characterization of a conjugated chimeric oligonucleotide-PEG-peptide. Eur. J. Org. Chem. 2002, 2002, 3473-3480. https://doi.org/10.1002/1099-0690(200210)2002:20<3473::Aid-ejoc3473>3.0.Co;2-2.
49 J. C. Bologna; Vives, E.; Imbach, J. L.; Morvan, F. Uptake and quantification of intracellular concentration of lipophilic pro-oligonucleotides in HeLa cells. Antisense Nucleic Acid Drug Dev. 2002, 12, 33-41. https://doi.org/10.1089/108729002753670247.
48 T. Guerlavais; Meyer, A.; Imbach, J. L.; Morvan, F. Use of 2-(tert-butyldiphenylsilyloxymethyl) benzoyl as N-protecting group for the synthesis of prooligonucleotides. Bioorg. Med. Chem. Lett. 2001, 11, 2813-2816. https://doi.org/10.1016/s0960-894x(01)00515-7.
47 J. C. Bres; Morvan, F.; Lefebvre, I.; Vasseur, J. J.; Pompon, A.; Imbach, J. L. Kinetics study of the biotransformation of an oligonucleotide prodrug in cells extract by matrix-assisted laser desorption-ionization time-of-flight mass spectrometry. J. Chromatogr. B 2001, 753, 123-130. https://doi.org/10.1016/s0378-4347(00)00502-8.
46 M. Ballico; Drioli, S.; Morvan, F.; Xodo, L.; Bonora, G. M. Triple, MPEG-conjugated, helix-forming oligonucleotides (TRIPEGXs): Liquid-phase synthesis of natural and chimeric “all-purine” sequences linked to high molecular weight poly(ethylene glycols). Bioconjugate Chem. 2001, 12, 719-725. https://doi.org/10.1021/bc010034b.
45 G. Tosquellas; Bryksin, A.; Alvarez, K.; Morvan, F.; Vasseur, J. J.; Rayner, B.; Rykova, E.; Laktionov, P.; Vlassov, V.; Imbach, J. L. Prooligonucleotides exhibit less serum-protein binding than phosphodiester and phosphorothioate oligonucleotides. Nucleosides Nucleotides Nucleic Acids 2000, 19, 995-1003. https://doi.org/10.1080/15257770008033038.
44 J. C. Bologna; Imbach, J. L.; Morvan, F. A mild method for fluorescein labeling of base-sensitive oligonucleotides on solid support. Tetrahedron Lett. 2000, 41, 7317-7321. https://doi.org/10.1016/s0040-4039(00)01227-2.
43 E. Vives; Dell’Aquila, C.; Bologna, J. C.; Morvan, F.; Rayner, B.; Imbach, J. L. Lipophilic pro-oligonucleotides are rapidly and efficiently internalized in HeLa cells. Nucleic Acids Res. 1999, 27, 4071-4076. https://doi.org/10.1093/nar/27.20.4071.
42 J. C. Bologna; Morvan, F.; Imbach, J. L. The prooligonucleotide approach: Synthesis of mixed phosphodiester and SATE phosphotriester prooligonucleotides using H-phosphonate and phosphoramidite chemistries. Eur. J. Org. Chem. 1999, 1999, 2353-2358.
41 G. Tosquellas; Bologna, J. C.; Morvan, F.; Rayner, B.; Imbach, J. L. First synthesis of alternating SATE-phosphotriester/phosphodiester prooligonucleotides on solid support. Bioorg. Med. Chem. Lett. 1998, 8, 2913-2918. https://doi.org/10.1016/s0960-894x(98)00518-6.
40 G. Tosquellas; Alvarez, K.; Dell’Aquila, C.; Morvan, F.; Vasseur, J. J.; Imbach, J. L.; Rayner, B. The pro-oligonucleotide approach: solid phase synthesis and preliminary evaluation of model pro-dodecathymidylates. Nucleic Acids Res. 1998, 26, 2069-2074. https://doi.org/10.1093/nar/26.9.2069.
39 F. Morvan; Zeidler, J.; Rayner, B. alpha-oligodeoxynucleotides containing 5-propynyl analogs of alpha-deoxyuridine and alpha-deoxycytidine: Synthesis and base pairing properties. Tetrahedron 1998, 54, 71-82. https://doi.org/10.1016/s0040-4020(97)10257-5.
38 S. VichierGuerre; Morvan, F.; Fulcrand, G.; Rayner, B. Boundary between DNA and enantio-DNA as a mimic of B-Z junction. Tetrahedron Lett. 1997, 38, 93-96. https://doi.org/10.1016/s0040-4039(96)02223-x.
37 G. Tosquellas; Morvan, F.; Rayner, B.; Imbach, J. L. The prooligonucleotide approach .4. Synthesis of chimeric prooligonucleotides with 6 enzymolabile masking groups and unexpected desulfurization side reaction. Bioorg. Med. Chem. Lett. 1997, 7, 263-268. https://doi.org/10.1016/s0960-894x(96)00616-6.
36 F. Morvan; Imbach, J. L.; Rayner, B. Comparative stability of eight different triple helices formed by differently modified DNA or RNA pyrimidine strands and a DNA hairpin. Antisense Nucleic Acid Drug Dev. 1997, 7, 327-334. https://doi.org/10.1089/oli.1.1997.7.327.
35 N. Mignet; Tosquellas, G.; Barber, I.; Morvan, F.; Rayner, B.; Imbach, J. L. The prooligonucleotide approach: Synthesis and stability of chimeric prooligonucleotides in culture medium and in total cell extract. New J. Chem. 1997, 21, 73-79.
34 N. Mignet; Morvan, F.; Rayner, B.; Imbach, J. L. The pro-oligonucleotide approach .5. Influence of the phosphorus atom environment on the hydrolysis of enzymolabile dinucleoside phosphotriesters. Bioorg. Med. Chem. Lett. 1997, 7, 851-854. https://doi.org/10.1016/s0960-894x(97)00106-6.
33 G. Tosquellas; Barber, I.; Morvan, F.; Rayner, B.; Imbach, J. L. The prooligonucleotide approach .3. Synthesis and bioreversibility of a chimeric phosphorodithioate prooligonucleotide. Bioorg. Med. Chem. Lett. 1996, 6, 457-462. https://doi.org/10.1016/0960-894x(96)00051-0.
32 F. Morvan; Sanghvi, Y. S.; Perbost, M.; Vasseur, J. J.; Bellon, L. Oligonucleotide mimics for antisense therapeutics: Solution phase and automated solid-support synthesis of MMI linked oligomers. J. Am. Chem. Soc. 1996, 118, 255-256. https://doi.org/10.1021/ja9533959.
31 F. Morvan; Chaix, C.; Rayner, B.; Imbach, J. L. Effect of 5-methylcytosine and 5-bromouracil in alpha-oligodeoxyribonucleotides on the stability of alpha beta beta triple helices. New J. Chem. 1996, 20, 589-593.
30 Y. I. Alekseev; Krynetskaya, N. F.; Tashlytsky, V. N.; Oretskaya, T. S.; Dolinnaya, N. G.; Morvan, F.; Rayner, B.; Malvy, C.; Shabarova, Z. A. Interaction of Escherichia coli ribonuclease H with hybrid duplexes containing 2′-deoxyxylothymidine, 2′-deoxy-2’fluorouridine or alpha-thymidine. Nucleosides Nucleotides 1996, 15, 1545-1558. https://doi.org/10.1080/07328319608002453.
29 M. Perbost; Hoshiko, T.; Morvan, F.; Swayze, E.; Griffey, R. H.; Sanghvi, Y. S. Synthesis of 5′-O-amino-2′-deoxypyrimidine and purine nucleosides – building-blocks for antisense oligonucleosides. J. Org. Chem. 1995, 60, 5150-5156. https://doi.org/10.1021/jo00121a037.
28 C. Leydier; Bellon, L.; Barascut, J. L.; Morvan, F.; Rayner, B.; Imbach, J. L. 4′-thio-RNA – Synthesis of mixed base 4′-thio-oligoribonucleotides, nuclease resistance, and base-pairing properties with complementary single and double-strand. Antisense Res. Dev. 1995, 5, 167-174. https://doi.org/10.1089/ard.1995.5.167.
27 I. Barber; Tosquellas, G.; Morvan, F.; Rayner, B.; Imbach, J. L. The prooligonucleotide approach .2. Synthesis and stability studies of chimeric oligonucleotide models. Bioorg. Med. Chem. Lett. 1995, 5, 1441-1444. https://doi.org/10.1016/0960-894x(95)00253-p.
26 H. Tanaka; Vickart, P.; Bertrand, J. R.; Rayner, B.; Morvan, F.; Imbach, J. L.; Paulin, D.; Malvy, C. Sequence-specific interaction of alpha.Beta-anomeric double-stranded DNA with the p50 subunit of NF-kappa-B – Application to the decoy approach. Nucleic Acids Res. 1994, 22, 3069-3074. https://doi.org/10.1093/nar/22.15.3069.
25 F. Morvan; Porumb, H.; Degols, G.; Lefebvre, I.; Pompon, A.; Sproat, B. S.; Rayner, B.; Malvy, C.; Lebleu, B.; Imbach, J. L. Comparative-evaluation of 7 oligonucleotide analogs as potential antisense agents. J. Med. Chem. 1993, 36, 280-287. https://doi.org/10.1021/jm00054a013.
24 G. Maury; Divita, G.; Morvan, F.; Imbach, J. L.; Goody, R. S. Rapid-determination of the affinity of 28-mer and 14-mer phosphorothioate oligonucleotides for HIV-1 reverse-transcriptase by fluorescence spectroscopy. Biochimica Et Biophysica Acta 1993, 1216, 1-8. https://doi.org/10.1016/0167-4781(93)90030-h.
23 J. Liquier; Letellier, R.; Dagneaux, C.; Ouali, M.; Morvan, F.; Raynier, B.; Imbach, J. L.; Taillandier, E. Triple-helix formation by alpha-oligodeoxynucleotides – a vibrational spectroscopy and molecular modeling study. Biochemistry 1993, 32, 10591-10598. https://doi.org/10.1021/bi00091a008.
22 G. Maury; Elalaoui, A.; Morvan, F.; Muller, B.; Imbach, J. L.; Goody, R. S. Template – phosphorothioate oligonucleotides duplexes as inhibitors of HIV-1 reverse-transcriptase. Biochem. Biophys. Res. Commun. 1992, 186, 1249-1256. https://doi.org/10.1016/s0006-291x(05)81540-2.
21 W. H. Gmeiner; Rayner, B.; Morvan, F.; Imbach, J. L.; Lown, J. W. Structure and conformation in solution of the parallel-stranded hybrid alpha-D(CGCAATTCGC) .beta-D(GCGTTAAGCG) by high-resolution 2D NMR. J. Biomol. NMR 1992, 2, 275-288. https://doi.org/10.1007/bf01875321.
20 L. Bellon; Morvan, F.; Barascut, J. L.; Imbach, J. L. Sugar modified oligonucleotides – Synthesis, nuclease resistance and base-pairing of oligodeoxynucleotides containing 1-(4′-thio-beta-D-ribofuranosyl)-thymine. Biochem. Biophys. Res. Commun. 1992, 184, 797-803. https://doi.org/10.1016/0006-291x(92)90660-d.
19 M. Azymah; Chavis, C.; Lucas, M.; Morvan, F.; Imbach, J. L. Isotactic glycero oligothymidylate – a convenient preparation of (r)-1′,2′-seco-2′-northymidine and (s)-1′,2′-seco-2′-northymidine. Nucleosides Nucleotides 1992, 11, 1241-1255. https://doi.org/10.1080/07328319208018339.
18 F. Morvan; Rayner, B.; Imbach, J. L. Alpha-oligonucleotides – a unique class of modified chimeric nucleic-acids. Anti-Cancer Drug Des. 1991, 6, 521-529.
17 B. Rayner; Matsukura, M.; Morvan, F.; Cohen, J. S.; Imbach, J. L. Invitro anti-HIV activity of phosphorothioate alpha-anomeric oligodeoxynucleotides. Comptes Rendus Acad. Sci. Ser. III-Sci. Vie-Life Sci. 1990, 310, 61-64.
16 F. Morvan; Rayner, B.; Imbach, J. L. Modified oligonucleotides .4. Solid-phase synthesis and preliminary evaluation of phosphorothioate RNA as potential antisense agents. Tetrahedron Lett. 1990, 31, 7149-7152. https://doi.org/10.1016/s0040-4039(00)97264-2.
15 F. Morvan; Genu, C.; Rayner, B.; Gosselin, G.; Imbach, J. L. Sugar modified oligonucleotides .3.1. Synthesis, nuclease resistance and base-pairing properties of alpha-L-octathymidylates and beta-L-octathymidylates. Biochem. Biophys. Res. Commun. 1990, 172, 537-543. https://doi.org/10.1016/0006-291x(90)90706-s.
14 W. H. Gmeiner; Rao, K. E.; Rayner, B.; Vasseur, J. J.; Morvan, F.; Imbach, J. L.; Lown, J. W. Polarity of annealing and structural-analysis of the RNase H resistant alpha-5′-d TACACA .beta-5′-r AUGUGU hybrid Determined By high-field H-1, C-13, and P-31 NMR analysis. Biochemistry 1990, 29, 10329-10341. https://doi.org/10.1021/bi00497a007.
13 R. Pauwels; Debyser, Z.; Balzarini, J.; Baba, M.; Desmyter, J.; Rayner, B.; Morvan, F.; Imbach, J. L.; De Clercq, E. Alpha-oligodeoxynucleotides as inhibitors of HIV reverse-transcriptase. Nucleosides Nucleotides Nucleic Acids 1989, 8, 995-1000. https://doi.org/10.1080/07328318908054262.
12 J. Paoletti; Bazile, D.; Morvan, F.; Imbach, J. L.; Paoletti, C. ALPHA-DNA .8. Thermodynamic parameters of complexes formed between the oligo-alpha-deoxynucleotides – alpha-D(GGAAGG) and alpha-D(CCTTCC) and their complementary oligo-beta-deoxynucleotides – beta-D(CCTTCC) and beta-D(GGAAGG) are different. Nucleic Acids Res. 1989, 17, 2693-2704. https://doi.org/10.1093/nar/17.7.2693.
11 J. L. Imbach; Rayner, B.; Morvan, F. Sugar-modified oligonucleotides – synthesis, physicochemical and biological properties. Nucleosides Nucleotides 1989, 8, 627-648. https://doi.org/10.1080/07328318908054204.
10 S. Thenet; Morvan, F.; Bertrand, J. R.; Gautie, C.; Malvy, C. Alpha are more stable than beta anomer oligonucleotides in 3T3 cellular-extracts. Biochimie 1988, 70, 1729-1732. https://doi.org/10.1016/0300-9084(88)90031-4.
9 F. Morvan; Rayner, B.; Leonetti, J. P.; Imbach, J. L. ALPHA-DNA .7. Solid-phase synthesis of alpha-anomeric oligodeoxyribonucleotides. Nucleic Acids Res. 1988, 16, 833-848. https://doi.org/10.1093/nar/16.3.833.
8 E. Bloch; Lavignon, M.; Bertrand, J. R.; Pognan, F.; Morvan, F.; Malvy, C.; Rayner, B.; Imbach, J. L.; Paoletti, C. Alpha-anomeric DNA – BETA-RNA hybrids as new synthetic inhibitors of Escherichia-coli RNase-H, Drosophila Embryo RNase-H and M-MLV reverse-transcriptase. Gene 1988, 72, 349-360. https://doi.org/10.1016/0378-1119(88)90162-x.
7 T. A. Bacon; Morvan, F.; Rayner, B.; Imbach, J. L.; Wickstrom, E. Alpha-oligodeoxynucleotide stability in serum, subcellular extracts and culture media. J. Biochem. Biophys. Methods 1988, 16, 311-318. https://doi.org/10.1016/0165-022x(88)90065-6.
6 F. Morvan; Rayner, B.; Imbach, J. L.; Thenet, S.; Bertrand, J. R.; Paoletti, J.; Malvy, C.; Paoletti, C. ALPHA-DNA-II – synthesis of unnatural alpha-anomeric oligodeoxyribonucleotides containing the 4 usual bases and study of their substrate activities for nucleases. Nucleic Acids Res. 1987, 15, 3421-3437. https://doi.org/10.1093/nar/15.8.3421.
5 F. Morvan; Rayner, B.; Imbach, J. L.; Lee, M.; Hartley, J. A.; Chang, D. K.; Lown, J. W. ALPHA-DNA-V – parallel annealing, handedness and conformation of the duplex of the unnatural alpha-hexadeoxyribonucleotide alpha- D(CpApTpGpCpG) with its beta-complement BETA- D(GpTpApCpGpC) deduced from high-field H-1-NMR. Nucleic Acids Res. 1987, 15, 7027-7044. https://doi.org/10.1093/nar/15.17.7027.
4 F. Morvan; Rayner, B.; Imbach, J. L.; Chang, D. K.; Lown, J. W. ALPHA-DNA-III – characterization by high-field H-1-NMR, anti-parallel self-recognition and conformation of the unnatural hexadeoxyribonucleotides alpha- D(CPAPTPGPCPG) and alpha- D(CPGPCPAPTPG) – alpha-oligodeoxynucleotides as potential cellular probes for gene-control. Nucleic Acids Res. 1987, 15, 4241-4255. https://doi.org/10.1093/nar/15.10.4241.
3 C. Gautier; Morvan, F.; Rayner, B.; Huynhdinh, T.; Igolen, J.; Imbach, J. L.; Paoletti, C.; Paoletti, J. ALPHA-DNA .4. Alpha-anomeric and beta-anomeric tetrathymidylates covalently linked to intercalating oxazolopyridocarbazole – synthesis, physicochemical properties and poly (rA) binding. Nucleic Acids Res. 1987, 15, 6625-6641. https://doi.org/10.1093/nar/15.16.6625.
2 C. Gagnor; Bertrand, J. R.; Thenet, S.; Lemaitre, M.; Morvan, F.; Rayner, B.; Malvy, C.; Lebleu, B.; Imbach, J. L.; Paoletti, C. ALPHA-DNA-VI – comparative-study of alpha-anomeric and beta-anomeric oligodeoxyribonucleotides in hybridization to messenger-RNA and in cell free translation inhibition. Nucleic Acids Res. 1987, 15, 10419-10436. https://doi.org/10.1093/nar/15.24.10419.
1 F. Morvan; Rayner, B.; Imbach, J. L.; Chang, D. K.; Lown, J. W. ALPHA-DNA .1. Synthesis, characterization by high-field H-1-NMR, and base-pairing properties of the unnatural hexadeoxyribonucleotide alpha- D(CPCPTPTPCPC) with its complement Beta- D(GPGPAPAPGPG). Nucleic Acids Res. 1986, 14, 5019-5035. https://doi.org/10.1093/nar/14.12.5019.